Why book with us?
Choose from exclusive hotel collection
We offer thousands of Port Isabel hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.
Enjoy seamless booking experience
Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.
Benefit from flexible travel options
We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.
Welcome to Port Isabel
Get ready to experience the charm and beauty of Port Isabel! Nestled along the Texas Gulf Coast, this picturesque town is rich in history and offers something for everyone. Explore the historic lighthouse, take a scenic boat tour, or simply relax on the sandy shores. Immerse yourself in the vibrant local culture and indulge in fresh, delicious seafood. Visit Port Isabel and discover the perfect blend of relaxation and adventure!
What our users say about Port Isabel hotels
Save time on your trip arrangements by booking one of our hand-picked hotels
Travelers’ choice
- Bayfront Cottage- Pool - Hot Tub - Close To Beach
- Anchors Away At North Shore
- Family Tides Villa
- Long Island Village Unit 347
- Deck And Pool Access Long Island Village Escape!
- Long Island Village Unit 831
- Beach Houses #1533
- Long Island Village 233 Conch Dr
- Harbor Island Retreat Villa
- Casa Sharay Villa
- Furnished Deck Waterfront Port Isabel Cottage!
- 495 W Clam Cir Villa
- Canalfront Port Isabel Cottage 5 Mi To Beach!
- Copper Bottomed Waterfront Cottage Bring The Family Please See Manager Info Before Booking
- Waterfront Port Isabel Getaway Bring Your Pet!
- Spacious 3Br Home Near Spi Beach & Restaurants
- Waterfront Home With Pool Spacious Bay , Sleeps 16
- Waterfront Port Isabel Family Home With Pool And Pier!
- Family-Friendly Resort Cottage With Private Patio
- Long Island Village Unit 349 Sand Dollar Dr
- Deck, Fire Pit And Grill Port Isabel Home!
- Charming 1Br Waterfront Retreat With Private Patio Villa
- Heron'S Sea Cottage With View Of Space X And Just Minutes From South Padre Island
- 5 Mi To Beach Pet-Friendly Port Isabel Home!
- Modern Port Isabel Home Coastal Family Home!
- New Luxury Waterfront Home, With Pool, Sleeps 20
- 4 Mi To Beach Home With Pool And Golf In Port Isabel!
- Bayside Waterfront Home With Private Patio
- Resort-Style Perks And Deck At Port Isabel Home!
- Waterfront 5 Bedroom Home W Private Pool
- Relaxing Gulf Coast Getaway With A Waterfront Deck Villa
- Long Island Village Texas
- Casa Sol Y Mar Villa
- 4000Sf Waterfront Home, With Pool, Sleeps 20
- Soft Serenity
- Modern Waterfront Escape With A Deck & Bbq Grill Apartment
- Clam Circle Retreat On The Laguna- Liv Resort
- Channelfront Remodeled Pool Boatslips
- 5 Mi To Beaches Sunny Port Isabel Golf Retreat
- Liv Resort, Private Jacuzzi And Pet Friendly
- Long Island Village Conch Unit 1
- Picturesque Texas Gulf Coast Home In Port Isabel!
- New Waterfront Bungalow Fisherman'S Paradise
- Bay Sunset Views Waterfront Pool Boat Slip Apartment
- 8 Mins To Spi Beach Spacious 3Br With Backyard
- Canal Front Retreat W Boat Dock & Coastal Views